CISD3

Across TCGA patient cohorts, CISD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,091 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CISD3-associated proteins across cancer lineages are TACO1, BASP1, and AKAP1. Each is linked with CISD3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CISD3-to-partner and partner-to-CISD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISD3 versus TACO1 in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CISD3→partner) and Y-score (partner→CISD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TACO1 →	+0.357	+0.408	<.001	<.001	3	5
LSCC	BASP1 →	-0.671	-0.435	<.001	<.001	3	5
LSCC	AKAP1 →	+0.406	+0.556	<.001	<.001	3	5
LUAD	AKAP1_S592 →	+0.881	+0.531	<.001	<.001	3	5
BRCA	WIPF2 →	+0.358	+0.596	<.001	.001	3	5
CCRCC	HEATR5B →	+0.207	+0.500	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,091 associations by consensus.

CISD3 vs TACO1 — LSCC

Explore this scatter interactively →