CISD2

Across TCGA patient cohorts, CISD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,002 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CISD2-associated proteins across cancer lineages are SPATA5, CASP6, and G3BP2. Each is linked with CISD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CISD2-to-partner and partner-to-CISD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISD2 versus SPATA5 in COAD, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CISD2→partner) and Y-score (partner→CISD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SPATA5 →	+0.227	+0.596	.001	<.001	3	4
OV	CASP6 →	+0.408	+0.501	.003	.001	3	4
COAD	G3BP2 →	+0.197	+0.457	.001	.002	3	4
OV	ANKRD17 →	+0.387	+0.532	<.001	.004	3	4
PDAC	RIPK1_S320 →	+0.493	+0.269	<.001	<.001	3	3
COAD	SPTBN1_T999 →	-0.374	-0.345	.004	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,002 associations by consensus.

CISD2 vs SPATA5 — COAD

Explore this scatter interactively →