CISD1

Across TCGA patient cohorts, CISD1 RNA expression is significantly associated with the RNA expression of many other genes, with 17,987 significant associations in total. ACC shows the largest number of these associations.

The most reproducible CISD1-associated genes across cancer lineages are UQCRFS1, SUCLG1, and MRPS16. Each is linked with CISD1 in more than 30 cancer types. Because this analysis shows association rather than direction, both CISD1-to-partner and partner-to-CISD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISD1 versus UQCRFS1 in ACC, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CISD1→partner) and Y-score (partner→CISD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	UQCRFS1 →	+1.178	+1.128	<.001	<.001	3	31
ACC	SUCLG1 →	+0.968	+1.036	<.001	<.001	3	31
ACC	MRPS16 →	+0.964	+1.133	<.001	<.001	3	31
TGCT	NDUFAB1 →	+0.819	+0.503	<.001	<.001	3	31
SCLC	VDAC2 →	+1.303	+0.643	<.001	<.001	3	30
UVM	CYCS →	+1.320	+0.937	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,987 associations by consensus.

CISD1 vs UQCRFS1 — ACC

Explore this scatter interactively →