CISD1

Across TCGA patient cohorts, CISD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,321 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CISD1-associated proteins across cancer lineages are CCDC6_S52, CDK1, and VDAC2. Each is linked with CISD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CISD1-to-partner and partner-to-CISD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISD1 versus CCDC6_S52 in PDAC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CISD1→partner) and Y-score (partner→CISD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CCDC6_S52 →	+0.618	+0.330	.004	.002	3	5
BRCA	CDK1 →	+0.665	+0.447	.001	<.001	3	5
CCRCC	VDAC2 →	+0.478	+0.566	<.001	.001	3	5
GBM	KIFBP →	+0.349	+0.554	<.001	<.001	3	4
LSCC	OCIAD1_S108 →	+0.905	+0.524	.001	<.001	3	4
LUAD	SUPV3L1 →	+0.386	+0.297	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,321 associations by consensus.

CISD1 vs CCDC6_S52 — PDAC

Explore this scatter interactively →