CISD1

Across TCGA patient cohorts, CISD1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,092 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CISD1-associated genes across cancer lineages are SERPINH1, CYTOR, and COL6A3. Each is linked with CISD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CISD1-to-partner and partner-to-CISD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISD1 versus SERPINH1 in UCEC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CISD1→partner) and Y-score (partner→CISD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SERPINH1 →	-0.841	-0.390	<.001	<.001	3	7
GBM	CYTOR →	-0.627	-0.506	.001	<.001	3	6
GBM	COL6A3 →	-1.797	-0.527	<.001	<.001	3	6
BRCA	ZEB2 →	-0.619	-0.362	.001	.007	3	6
OV	COL5A2 →	-1.039	-0.452	.005	<.001	3	6
OV	FAP →	-1.302	-0.450	.009	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,092 associations by consensus.

CISD1 vs SERPINH1 — UCEC

Explore this scatter interactively →