CISD1

Across TCGA cell cohorts, CISD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,476 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CISD1-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, DAMP biosynthetic process, and Purine deoxyribonucleoside monophosphate biosynthetic process. Each is linked with CISD1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CISD1-to-partner and partner-to-CISD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by CISD1-low versus CISD1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CISD1→partner) and Y-score (partner→CISD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.131	+1.086	.006	.001	2	13
LIVER	DAMP biosynthetic process →	+0.127	+0.847	<.001	<.001	3	11
LIVER	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.127	+0.847	<.001	<.001	3	11
BLOOD_Myeloma	Protein localization to kinetochore →	+0.133	+1.217	<.001	.002	3	9
LUNG_NSCLC_LUAD	Response to vitamin B6 →	+0.116	+0.480	<.001	.002	3	9
BREAST	Single strand break repair →	+0.075	+0.661	<.001	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,476 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by CISD1 expression — BLOOD_Myeloma

Explore this box plot interactively →