CIRBP

Across TCGA patient cohorts, CIRBP protein abundance is significantly associated with the RNA expression of many other genes, with 20,114 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CIRBP-associated genes across cancer lineages are G0S2, CXCL8, and IL1A. Each is linked with CIRBP in more than 6 cancer types. Because this analysis shows association rather than direction, both CIRBP-to-partner and partner-to-CIRBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CIRBP versus G0S2 in GBM, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIRBP→partner) and Y-score (partner→CIRBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	G0S2 →	-1.986	-0.532	<.001	<.001	3	6
GBM	CXCL8 →	-2.601	-0.602	<.001	<.001	3	6
HNSC	IL1A →	-1.468	-0.341	.001	.001	3	6
LUAD	KYNU →	-1.102	-0.349	<.001	<.001	3	6
BRCA	NRDE2 →	+0.342	+0.410	<.001	<.001	3	6
BRCA	FAM161B →	+0.869	+0.541	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,114 associations by consensus.

CIRBP vs G0S2 — GBM

Explore this scatter interactively →