CIRBP

Across TCGA cell cohorts, CIRBP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,201 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CIRBP-associated GO terms across cancer lineages are Low-density lipoprotein particle clearance, Peptide antigen transport, and Forebrain radial glial cell differentiation. Each is linked with CIRBP in more than 8 cancer types. Because this analysis shows association rather than direction, both CIRBP-to-partner and partner-to-CIRBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Low-density lipoprotein particle clearance grouped by CIRBP-low versus CIRBP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CIRBP→partner) and Y-score (partner→CIRBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Low-density lipoprotein particle clearance →	-0.182	-0.928	.003	.001	3	9
BONE	Peptide antigen transport →	-0.868	-0.752	.005	.002	3	9
BONE	Forebrain radial glial cell differentiation →	+0.212	+1.321	<.001	<.001	3	7
BONE	Podocyte development →	-0.315	-1.026	.002	.001	3	7
BREAST	Response to L-phenylalanine derivative →	-0.117	-0.799	.006	.002	2	8
UPPER_AERODIGESTIVE_TRACT	Hemidesmosome assembly →	-0.167	-0.859	.005	.003	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,201 associations by consensus.

Low-density lipoprotein particle clearance by CIRBP expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →