CIRBP

Across TCGA cell cohorts, CIRBP mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CIRBP-associated genes across cancer lineages are C10orf53 and CDRT15L2. Each is linked with CIRBP in more than 1 cancer types. Because this analysis shows association rather than direction, both CIRBP-to-partner and partner-to-CIRBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by CIRBP-low versus CIRBP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIRBP→partner) and Y-score (partner→CIRBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C10orf53 →	+0.015	+4.217	<.001	.001	3	1
OVARY	CDRT15L2 →	+0.022	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

C10orf53 by CIRBP expression — LARGE_INTESTINE

Explore this box plot interactively →