CIR1P1

Across TCGA patient cohorts, CIR1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,594 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CIR1P1-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Regulation of DNA recombination, and Viral translation. Each is linked with CIR1P1 in more than 15 cancer types. Because this analysis shows association rather than direction, both CIR1P1-to-partner and partner-to-CIR1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by CIR1P1-low versus CIR1P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CIR1P1→partner) and Y-score (partner→CIR1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of double-strand break repair via homologous recombination →	+0.051	+0.251	<.001	<.001	3	16
STAD	Regulation of DNA recombination →	+0.049	+0.266	<.001	<.001	3	14
STAD	Viral translation →	+0.067	+0.265	<.001	<.001	3	14
STAD	Regulation of protein ubiquitination →	+0.061	+0.284	<.001	<.001	3	14
STAD	Mitochondrial translation →	+0.069	+0.274	<.001	<.001	3	14
ESCA	Mitochondrial gene expression →	+0.077	+0.317	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,594 associations by consensus.

Regulation of double-strand break repair via homologous recombination by CIR1P1 expression — STAD

Explore this box plot interactively →