CIR1

Across TCGA patient cohorts, CIR1 protein abundance is significantly associated with the protein abundance of many other proteins, with 34,230 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CIR1-associated proteins across cancer lineages are SNRPB2, SART1, and SF3A2. Each is linked with CIR1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CIR1-to-partner and partner-to-CIR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CIR1 versus SNRPB2 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CIR1→partner) and Y-score (partner→CIR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNRPB2 →	+0.290	+0.309	<.001	.001	3	8
LSCC	SART1 →	+0.250	+0.235	<.001	<.001	3	7
OV	SF3A2 →	+0.353	+0.643	<.001	<.001	3	7
OV	SF3B6 →	+0.324	+0.594	<.001	<.001	3	7
OV	SSB →	+0.426	+0.463	<.001	<.001	3	7
BRCA	GPATCH8 →	+0.369	+0.380	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 34,230 associations by consensus.

CIR1 vs SNRPB2 — BRCA

Explore this scatter interactively →