CIR1

Across TCGA patient cohorts, CIR1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CIR1-associated genes across cancer lineages are Osteoblast. Each is linked with CIR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CIR1-to-partner and partner-to-CIR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoblast grouped by CIR1-low versus CIR1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIR1→partner) and Y-score (partner→CIR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Osteoblast →	+0.047	+4.035	<.001	.012	3	2

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Osteoblast by CIR1 expression — HNSC

Explore this box plot interactively →