CIR1

Across TCGA cell cohorts, CIR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,879 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CIR1-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and COPII-coated vesicle budding. Each is linked with CIR1 in more than 13 cancer types. Because this analysis shows association rather than direction, both CIR1-to-partner and partner-to-CIR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by CIR1-low versus CIR1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CIR1→partner) and Y-score (partner→CIR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Process utilizing autophagic mechanism →	+0.050	+0.560	<.001	<.001	3	14
SOFT_TISSUE	Autophagy →	+0.050	+0.560	<.001	<.001	3	14
SKIN	COPII-coated vesicle budding →	+0.076	+0.691	<.001	<.001	3	13
SKIN	Negative regulation of hematopoietic stem cell differentiation →	+0.142	+0.832	.002	.001	3	13
CNS	COPII vesicle coating →	+0.096	+0.697	<.001	<.001	3	13
PANCREAS	Macroautophagy →	+0.048	+0.598	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,879 associations by consensus.

Process utilizing autophagic mechanism by CIR1 expression — SOFT_TISSUE

Explore this box plot interactively →