Across TCGA patient cohorts, CIPC protein abundance is significantly associated with the RNA expression of many other genes, with 113 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CIPC-associated genes across cancer lineages are SLC25A1, ATP4A, and NCOA3. Each is linked with CIPC in more than 1 cancer types. Because this analysis shows association rather than direction, both CIPC-to-partner and partner-to-CIPC results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIPC→partner) and Y-score (partner→CIPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC25A1 →	+0.876	+0.543	.009	.005	3	1
BRCA	ATP4A →	+0.089	+0.387	.004	.008	3	1
BRCA	NCOA3 →	+0.814	+0.387	.003	.008	3	1
BRCA	GDF5 →	-0.929	-0.543	.001	.005	3	1
BRCA	APOL3 →	-1.266	-0.543	.002	.005	3	1
BRCA	KRT17P1 →	+0.117	+0.387	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 113 associations by consensus.

Exploration

CIPC survival (RNA) · tumor vs normal (RNA) · all CIPC data types