Across TCGA cell cohorts, CIPC RNA expression is significantly associated with the go_rna of many other GO terms, with 5,389 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CIPC-associated GO terms across cancer lineages are Regulation of DNA repair, Epigenetic regulation of gene expression, and Negative regulation of DNA-templated transcription, elongation. Each is linked with CIPC in more than 15 cancer types. Because this analysis shows association rather than direction, both CIPC-to-partner and partner-to-CIPC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CIPC→partner) and Y-score (partner→CIPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of DNA repair →	+0.089	+0.681	.001	<.001	3	16
BONE	Epigenetic regulation of gene expression →	+0.097	+0.706	<.001	<.001	3	16
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.158	+0.825	<.001	<.001	3	15
BONE	Heterochromatin organization →	+0.083	+0.550	.001	.003	3	15
BONE	Nucleic acid catabolic process →	+0.071	+0.771	<.001	<.001	3	14
BONE	Extracellular matrix organization →	-0.167	-0.492	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,389 associations by consensus.

Exploration

CIPC survival (RNA) · tumor vs normal (RNA) · all CIPC data types