CIP2A

Across TCGA cell cohorts, CIP2A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,352 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CIP2A-associated GO terms across cancer lineages are Protein localization to chromosome, Positive regulation of cell cycle, and Spindle elongation. Each is linked with CIP2A in more than 19 cancer types. Because this analysis shows association rather than direction, both CIP2A-to-partner and partner-to-CIP2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome grouped by CIP2A-low versus CIP2A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CIP2A→partner) and Y-score (partner→CIP2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to chromosome →	+0.135	+1.373	<.001	<.001	3	20
OESOPHAGUS	Positive regulation of cell cycle →	+0.113	+1.468	<.001	<.001	3	20
KIDNEY	Spindle elongation →	+0.222	+0.968	<.001	<.001	3	20
KIDNEY	Mitotic spindle midzone assembly →	+0.271	+1.317	<.001	<.001	3	20
OESOPHAGUS	Regulation of chromosome condensation →	+0.255	+1.631	<.001	<.001	3	20
BREAST	Meiotic nuclear division →	+0.058	+1.153	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,352 associations by consensus.

Protein localization to chromosome by CIP2A expression — OESOPHAGUS

Explore this box plot interactively →