CINP

Across TCGA patient cohorts, CINP mutation is significantly associated with the RNA expression of many other genes, with 217 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CINP-associated genes across cancer lineages are PFAS, NDUFA12, and LILRP1. Each is linked with CINP in more than 1 cancer types. Because this analysis shows association rather than direction, both CINP-to-partner and partner-to-CINP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PFAS grouped by CINP-low versus CINP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CINP→partner) and Y-score (partner→CINP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PFAS →	+0.694	+3.343	.003	.005	3	1
UCEC	NDUFA12 →	+0.517	+3.343	<.001	.005	3	1
UCEC	LILRP1 →	+0.138	+4.159	<.001	<.001	3	1
UCEC	HMX2 →	+1.059	+3.332	<.001	.005	3	1
UCEC	KEL →	+0.276	+3.450	.005	.004	3	1
UCEC	ABHD17AP1 →	+0.763	+3.343	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 217 associations by consensus.

PFAS by CINP expression — UCEC

Explore this box plot interactively →