CINP

Across TCGA cell cohorts, CINP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,740 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CINP-associated GO terms across cancer lineages are tRNA wobble cytosine modification, Oxidative RNA demethylation, and mRNA 3'-end processing by stem-loop binding and cleavage. Each is linked with CINP in more than 9 cancer types. Because this analysis shows association rather than direction, both CINP-to-partner and partner-to-CINP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA wobble cytosine modification grouped by CINP-low versus CINP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CINP→partner) and Y-score (partner→CINP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	tRNA wobble cytosine modification →	+0.083	+0.905	.004	.001	3	10
BONE	Oxidative RNA demethylation →	+0.110	+0.724	.001	.004	3	10
UPPER_AERODIGESTIVE_TRACT	mRNA 3'-end processing by stem-loop binding and cleavage →	+0.106	+0.710	.002	.005	3	10
OVARY	Activation of transmembrane receptor protein tyrosine kinase activity →	-0.237	-0.692	.007	.004	3	8
SKIN	tRNA wobble base modification →	+0.042	+0.443	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	tRNA 5'-leader removal →	+0.088	+0.817	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,740 associations by consensus.

tRNA wobble cytosine modification by CINP expression — BONE

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