CINP

Across TCGA cell cohorts, CINP mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CINP-associated genes across cancer lineages are DEFA3, C7orf77, and FCRL4. Each is linked with CINP in more than 1 cancer types. Because this analysis shows association rather than direction, both CINP-to-partner and partner-to-CINP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFA3 grouped by CINP-low versus CINP-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CINP→partner) and Y-score (partner→CINP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DEFA3 →	+0.155	+4.930	<.001	.008	3	1
SOFT_TISSUE	C7orf77 →	+0.152	+4.930	<.001	.008	3	1
OESOPHAGUS	FCRL4 →	+0.013	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

DEFA3 by CINP expression — SOFT_TISSUE

Explore this box plot interactively →