CILP

Across TCGA cell cohorts, CILP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,490 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CILP-associated GO terms across cancer lineages are ERAD pathway, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with CILP in more than 8 cancer types. Because this analysis shows association rather than direction, both CILP-to-partner and partner-to-CILP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERAD pathway grouped by CILP-low versus CILP-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CILP→partner) and Y-score (partner→CILP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ERAD pathway →	+0.056	+1.174	.002	.006	3	8
PANCREAS	Regulation of myoblast fusion →	+0.081	+0.054	<.001	.009	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.092	+0.100	.002	.004	2	9
PANCREAS	Cytoplasmic translation →	+0.079	+0.070	<.001	.006	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.090	+0.100	.002	.004	2	9
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.068	+0.058	<.001	.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,490 associations by consensus.

ERAD pathway by CILP expression — OVARY

Explore this box plot interactively →