CILP

Across TCGA cell cohorts, CILP mutation is significantly associated with the RNA expression of many other genes, with 742 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CILP-associated genes across cancer lineages are C1orf232, C19orf44, and C22orf23. Each is linked with CILP in more than 1 cancer types. Because this analysis shows association rather than direction, both CILP-to-partner and partner-to-CILP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf232 grouped by CILP-low versus CILP-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CILP→partner) and Y-score (partner→CILP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C1orf232 →	+0.031	+4.643	<.001	.005	3	2
LARGE_INTESTINE	C19orf44 →	+0.489	+2.652	<.001	.001	3	2
BLOOD_Leukemia	C22orf23 →	+0.218	+3.199	.004	.007	3	2
BLOOD_Leukemia	PCNX2 →	+1.390	+3.199	.002	.007	3	2
BLOOD_Leukemia	GID4 →	+0.678	+3.199	<.001	.007	3	2
BLOOD_Leukemia	FEM1A →	+0.645	+3.199	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 742 associations by consensus.

C1orf232 by CILP expression — BLOOD_Lymphoma

Explore this box plot interactively →