CILK1

Across TCGA patient cohorts, CILK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,004 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CILK1-associated proteins across cancer lineages are MNDA, PSME2, and VSIR. Each is linked with CILK1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CILK1-to-partner and partner-to-CILK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CILK1 versus MNDA in GBM, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CILK1→partner) and Y-score (partner→CILK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MNDA →	-0.662	-0.428	<.001	<.001	3	6
HNSC	PSME2 →	-0.366	-0.868	<.001	.003	3	6
UCEC	VSIR →	-0.435	-0.601	.002	<.001	3	5
LSCC	NUCB1_S369 →	-0.717	-0.830	<.001	<.001	3	5
LSCC	OTUD7B →	+0.249	+0.654	<.001	<.001	3	5
LSCC	POGZ →	+0.275	+0.704	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,004 associations by consensus.

CILK1 vs MNDA — GBM

Explore this scatter interactively →