CILK1

Across TCGA patient cohorts, CILK1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,535 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CILK1-associated genes across cancer lineages are SNRPD3, SLC25A15, and CORO2B. Each is linked with CILK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CILK1-to-partner and partner-to-CILK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CILK1 versus SNRPD3 in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CILK1→partner) and Y-score (partner→CILK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SNRPD3 →	+0.845	+0.503	<.001	<.001	3	2
LSCC	SLC25A15 →	+0.540	+0.442	.008	<.001	3	2
UCEC	CORO2B →	+0.908	+0.336	<.001	.006	3	2
BRCA	IDS →	+0.707	+0.534	<.001	<.001	3	2
LSCC	GCLC →	+1.459	+0.454	<.001	<.001	3	2
BRCA	FBXO30 →	+0.832	+0.377	.008	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,535 associations by consensus.

CILK1 vs SNRPD3 — LSCC

Explore this scatter interactively →