CILK1

Across TCGA cell cohorts, CILK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,561 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CILK1-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Intraciliary anterograde transport, and Positive regulation of pinocytosis. Each is linked with CILK1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CILK1-to-partner and partner-to-CILK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by CILK1-low versus CILK1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CILK1→partner) and Y-score (partner→CILK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of nucleotide-excision repair →	+0.103	+0.917	<.001	<.001	3	10
LARGE_INTESTINE	Intraciliary anterograde transport →	+0.094	+1.047	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of pinocytosis →	+0.110	+0.937	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Cytoskeleton-dependent intracellular transport →	+0.053	+1.356	.006	.004	3	9
OESOPHAGUS	Response to insulin →	+0.035	+0.635	.007	.008	2	10
LARGE_INTESTINE	Copper ion export →	-0.211	-1.117	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,561 associations by consensus.

Regulation of nucleotide-excision repair by CILK1 expression — BLOOD_Leukemia

Explore this box plot interactively →