Across TCGA patient cohorts, CIDEC mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CIDEC-associated genes across cancer lineages are ERK2, JNK_pT183_Y185, and p70-S6K. Each is linked with CIDEC in more than 1 cancer types. Because this analysis shows association rather than direction, both CIDEC-to-partner and partner-to-CIDEC results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIDEC→partner) and Y-score (partner→CIDEC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.195	+2.321	.044	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.204	-3.169	.016	.019	3	1
UCEC	p70-S6K →	+0.210	+2.827	.030	.035	3	1
UCEC	Tuberin →	+0.349	+3.459	.009	.005	3	1
UCEC	ATM →	-0.505	-3.459	.026	.005	3	1
UCEC	Caspase-7-cleavedD198 →	+1.057	+3.459	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

CIDEC survival (RNA) · tumor vs normal (RNA) · all CIDEC data types