CICP6

Across TCGA patient cohorts, CICP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,605 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CICP6-associated GO terms across cancer lineages are Positive regulation of DNA repair, Macromolecule deacylation, and Ribonucleoside monophosphate metabolic process. Each is linked with CICP6 in more than 7 cancer types. Because this analysis shows association rather than direction, both CICP6-to-partner and partner-to-CICP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by CICP6-low versus CICP6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CICP6→partner) and Y-score (partner→CICP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.035	+0.007	<.001	<.001	3	8
STAD	Macromolecule deacylation →	+0.029	+0.006	<.001	<.001	3	7
STAD	Ribonucleoside monophosphate metabolic process →	+0.047	+0.011	<.001	<.001	3	7
STAD	Obsolete histone methylation →	+0.035	+0.007	<.001	<.001	3	7
SKCM	Protein localization to nucleolus →	+0.046	+0.002	<.001	<.001	3	6
STAD	tRNA modification →	+0.034	+0.006	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,605 associations by consensus.

Positive regulation of DNA repair by CICP6 expression — STAD

Explore this box plot interactively →