CICP5

Across TCGA pan-cancer cohorts, CICP5 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CICP5’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CICP5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CICP5 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, THCA, and KICH are the cancer types where CICP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CICP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.016	.006	8	view →
THCA	All	All	−0.028	<.001	6	view →
KICH	All	All	−0.013	.020	3	view →
CHOL	All	II,III,IV	+0.215	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

CICP5–HNSC

Open the HNSC breakdown →