CICP27

Across TCGA patient cohorts, CICP27 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,897 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CICP27-associated GO terms across cancer lineages are Nucleolar large rRNA transcription by RNA polymerase I, Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and Negative regulation of DNA-templated transcription, elongation. Each is linked with CICP27 in more than 14 cancer types. Because this analysis shows association rather than direction, both CICP27-to-partner and partner-to-CICP27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleolar large rRNA transcription by RNA polymerase I grouped by CICP27-low versus CICP27-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CICP27→partner) and Y-score (partner→CICP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleolar large rRNA transcription by RNA polymerase I →	+0.053	+0.075	<.001	<.001	3	15
TGCT	Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.073	+0.493	<.001	<.001	3	14
ESCA	Negative regulation of DNA-templated transcription, elongation →	+0.053	+0.143	<.001	.001	2	15
STAD	Regulation of telomere maintenance in response to DNA damage →	+0.044	+0.073	<.001	<.001	3	14
STAD	Positive regulation of transcription by RNA polymerase I →	+0.053	+0.064	<.001	<.001	3	14
STAD	Base-excision repair →	+0.041	+0.058	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,897 associations by consensus.

Nucleolar large rRNA transcription by RNA polymerase I by CICP27 expression — STAD

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