Across TCGA pan-cancer cohorts, CICP17 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CICP17’s most consistent transcriptional readouts.
The strongest signal is observed in cholangiocarcinoma (CHOL), where CICP17 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CICP17 is over-expressed in tumor.
CHOL and KIRC are the cancer types where CICP17 tumor–normal differential expression is most reproducible.