CICP16

Across TCGA pan-cancer cohorts, CICP16 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CICP16’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CICP16 RNA is repressed in tumor relative to normal tissue. In most cancer types CICP16 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and LUSC are the cancer types where CICP16 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CICP16 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.314	<.001	10	view →
KICH	All	All	−0.158	.001	4	view →
LUSC	Female	II,III,IV	−0.244	.008	2	view →
READ	All	III,IV	+0.164	.038	2	view →
CHOL	All	All	+0.288	.012	1	view →
COAD	Female	III,IV	−0.204	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CICP16–THCA

Open the THCA breakdown →