CICP14

Across TCGA patient cohorts, CICP14 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CICP14-associated genes across cancer lineages are RNU6-382P, MIR5582, and MIR486-1. Each is linked with CICP14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CICP14-to-partner and partner-to-CICP14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-382P grouped by CICP14-low versus CICP14-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CICP14→partner) and Y-score (partner→CICP14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-382P →	+0.358	+8.471	<.001	.005	3	1
UCEC	MIR5582 →	+0.789	+3.717	<.001	.003	3	1
UCEC	MIR486-1 →	+0.824	+3.599	<.001	.007	3	1
UCEC	MIR8087 →	+0.569	+3.813	.007	.002	3	1
SKCM	RPS29P26 →	+0.718	+7.816	<.001	.008	3	1
UCEC	IGKV1OR-2 →	+0.401	+3.393	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

RNU6-382P by CICP14 expression — BRCA

Explore this box plot interactively →