Across TCGA pan-cancer cohorts, CICP13 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CICP13’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where CICP13 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CICP13 is over-expressed in tumor.
LIHC and KIRP are the cancer types where CICP13 tumor–normal differential expression is most reproducible.