CICP1

Across TCGA patient cohorts, CICP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,963 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CICP1-associated GO terms across cancer lineages are Negative regulation of TORC1 signaling, Mitochondrial membrane organization, and Macromolecule methylation. Each is linked with CICP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CICP1-to-partner and partner-to-CICP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of TORC1 signaling grouped by CICP1-low versus CICP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CICP1→partner) and Y-score (partner→CICP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of TORC1 signaling →	+0.070	+0.012	<.001	.003	3	4
ESCA	Mitochondrial membrane organization →	+0.082	+0.005	<.001	.002	3	4
ESCA	Macromolecule methylation →	+0.073	+0.005	<.001	.006	3	4
LUSC	Nucleophagy →	+0.083	+0.004	<.001	.001	3	4
HNSC	Organism emergence from protective structure →	+0.061	+0.003	<.001	.002	3	4
ESCA	Microtubule-based transport →	+0.055	+0.005	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,963 associations by consensus.

Negative regulation of TORC1 signaling by CICP1 expression — STAD

Explore this box plot interactively →