CIBAR2

Across TCGA patient cohorts, CIBAR2 mutation is significantly associated with the RNA expression of many other genes, with 2,923 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CIBAR2-associated genes across cancer lineages are MIR598, SMARCE1P4, and RNY1P8. Each is linked with CIBAR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CIBAR2-to-partner and partner-to-CIBAR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR598 grouped by CIBAR2-low versus CIBAR2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIBAR2→partner) and Y-score (partner→CIBAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR598 →	+0.301	+4.357	<.001	.001	3	2
COAD	SMARCE1P4 →	+0.232	+3.636	.008	.006	3	2
UCEC	RNY1P8 →	+0.292	+3.038	<.001	.006	3	2
UCS	RNU6-455P →	+0.462	+5.087	<.001	.006	3	1
UCS	RN7SL807P →	+0.200	+5.700	<.001	.002	3	1
UCS	H3P34 →	+0.129	+5.087	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,923 associations by consensus.

MIR598 by CIBAR2 expression — COAD

Explore this box plot interactively →