Across TCGA patient cohorts, CIBAR1 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CIBAR1-associated genes across cancer lineages are EGFR_pY1068, Fibronectin, and FOXO3a. Each is linked with CIBAR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CIBAR1-to-partner and partner-to-CIBAR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIBAR1→partner) and Y-score (partner→CIBAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.254	-2.459	.036	.020	3	1
UCEC	Fibronectin →	-0.422	-3.584	.008	.002	3	1
UCEC	FOXO3a →	+0.125	+2.472	.010	.011	3	1
UCEC	JNK2 →	+0.370	+3.179	<.001	.010	3	1
UCEC	p62 Lck ligand →	+0.336	+3.584	.032	.002	3	1
UCEC	Rictor_pT1135 →	-0.117	-3.000	.018	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

CIBAR1 survival (RNA) · tumor vs normal (RNA) · all CIBAR1 data types