CIB4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CIB4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,708 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CIB4-associated proteins across cancer lineages are MYEF2, INTS3, and PLS3. Each is linked with CIB4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CIB4-to-partner and partner-to-CIB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CIB4 versus MYEF2 in LSCC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CIB4→partner) and Y-score (partner→CIB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMYEF2 →+0.605+0.247<.001<.00135
GBMINTS3 →+0.212+0.296<.001.00134
GBMPLS3 →-0.476-0.240<.001<.00134
GBMPOGZ →+0.290+0.365.001<.00134
OVZMYM2 →+0.300+0.410<.001.00133
OVTBC1D22A →-0.268-0.393<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,708 associations by consensus.

CIB4 vs MYEF2 — LSCC

Per-sample scatter of CIB4 vs MYEF2 in LSCC (Pearson r = 0.58).

Explore this scatter interactively →

Exploration