CIB4

Across TCGA cell cohorts, CIB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,011 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CIB4-associated GO terms across cancer lineages are Regulation of action potential firing rate, Negative regulation of circadian rhythm, and Uridine metabolic process. Each is linked with CIB4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CIB4-to-partner and partner-to-CIB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of action potential firing rate grouped by CIB4-low versus CIB4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CIB4→partner) and Y-score (partner→CIB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of action potential firing rate →	+1.553	+0.155	<.001	.006	3	4
BREAST	Negative regulation of circadian rhythm →	+0.105	+0.332	.001	.006	3	4
BLOOD_Leukemia	Uridine metabolic process →	-0.829	-0.077	.001	.009	3	4
BLOOD_Leukemia	Pyrimidine ribonucleoside metabolic process →	-0.829	-0.077	.001	.009	3	4
BONE	Positive regulation of cell-substrate adhesion →	-0.137	-0.461	<.001	.007	3	3
BONE	Cellular response to aldehyde →	-0.190	-0.429	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,011 associations by consensus.

Regulation of action potential firing rate by CIB4 expression — BLOOD_Leukemia

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