CIB4

Across TCGA cell cohorts, CIB4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CIB4-associated genes across cancer lineages are BMP15 and CD300H. Each is linked with CIB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CIB4-to-partner and partner-to-CIB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMP15 grouped by CIB4-low versus CIB4-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIB4→partner) and Y-score (partner→CIB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	BMP15 →	+0.019	+5.754	<.001	.002	3	1
LARGE_INTESTINE	CD300H →	+0.045	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

BMP15 by CIB4 expression — CNS

Explore this box plot interactively →