CIAO2A

Across TCGA cell cohorts, CIAO2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,636 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CIAO2A-associated GO terms across cancer lineages are Mitochondrial translation, Mitochondrial gene expression, and Tricarboxylic acid cycle. Each is linked with CIAO2A in more than 11 cancer types. Because this analysis shows association rather than direction, both CIAO2A-to-partner and partner-to-CIAO2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by CIAO2A-low versus CIAO2A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CIAO2A→partner) and Y-score (partner→CIAO2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial translation →	+0.149	+0.899	<.001	<.001	3	12
BONE	Mitochondrial gene expression →	+0.140	+0.769	<.001	.002	3	10
LIVER	Tricarboxylic acid cycle →	+0.124	+0.664	<.001	<.001	3	10
SKIN	Mitochondrial respiratory chain complex assembly →	+0.058	+0.604	<.001	<.001	3	10
BONE	Quinone biosynthetic process →	+0.091	+0.637	.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Ubiquinone metabolic process →	+0.099	+1.007	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,636 associations by consensus.

Mitochondrial translation by CIAO2A expression — BONE

Explore this box plot interactively →