CIAO1

Across TCGA patient cohorts, CIAO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,672 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CIAO1-associated proteins across cancer lineages are P4HB, GTF3C4, and MYDGF. Each is linked with CIAO1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CIAO1-to-partner and partner-to-CIAO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CIAO1 versus P4HB in GBM, with a Pearson correlation of -0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CIAO1→partner) and Y-score (partner→CIAO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	P4HB →	-0.437	-0.210	<.001	<.001	3	5
LSCC	GTF3C4 →	+0.336	+0.346	<.001	<.001	3	5
LSCC	MYDGF →	-0.334	-0.317	<.001	<.001	3	4
LSCC	NUP188 →	+0.148	+0.313	<.001	<.001	3	4
LSCC	ORC4 →	+0.346	+0.340	<.001	<.001	3	4
LSCC	ORC5 →	+0.383	+0.341	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,672 associations by consensus.

CIAO1 vs P4HB — GBM

Explore this scatter interactively →