CHTOP

Across TCGA patient cohorts, CHTOP RNA expression is significantly associated with the protein abundance of many other proteins, with 19,978 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHTOP-associated proteins across cancer lineages are GATAD2B, RBM39, and RPRD2. Each is linked with CHTOP in more than 9 cancer types. Because this analysis shows association rather than direction, both CHTOP-to-partner and partner-to-CHTOP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHTOP versus GATAD2B in GBM, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHTOP→partner) and Y-score (partner→CHTOP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GATAD2B →	+0.387	+0.464	<.001	<.001	3	10
GBM	RBM39 →	+0.251	+0.333	<.001	<.001	3	8
LSCC	RPRD2 →	+0.339	+0.601	<.001	<.001	3	8
GBM	TCERG1 →	+0.272	+0.328	<.001	<.001	3	8
GBM	BUB3 →	+0.374	+0.440	<.001	<.001	3	8
UCEC	ADAR →	+0.395	+0.646	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,978 associations by consensus.

CHTOP vs GATAD2B — GBM

Explore this scatter interactively →