Q-omics provides the consensus-scored CHTF8P1 profile across patient tissues and cancer cell-line models. CHTF8P1 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, CHTF8P1 is differentially expressed in 4, with the highest sampling consensus in THCA. Additionally, CHTF8P1 RNA expression shows 6,749 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight COAD, THCA, and THYM as cancer lineages where CHTF8P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CHTF8P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CHTF8P1 survival associations across molecular data types. CHTF8P1 RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CHTF8P1 RNA expression–survival associations across cancer types. High CHTF8P1 expression shows unfavorable associations in LIHC, ACC and THCA, but favorable associations in COAD, ESCA and STAD. The COAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify COAD as the clearest survival context for CHTF8P1 RNA expression.
This table summarizes CHTF8P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for CHTF8P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CHTF8P1 shows lower tumor expression in THCA, KICH, BRCA and KIRC. The THCA box plot shows higher CHTF8P1 RNA expression in normal versus tumor tissue (log2 FC = −0.067, t-test p < 0.001).
This table shows molecular features associated with CHTF8P1 in patient tissues and cancer cell lines. In patient samples, CHTF8P1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
