CHST9

Across TCGA patient cohorts, CHST9 mutation is significantly associated with the RNA expression of many other genes, with 2,514 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHST9-associated genes across cancer lineages are PLLPP1, SNORA36A, and RMND1. Each is linked with CHST9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST9-to-partner and partner-to-CHST9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLLPP1 grouped by CHST9-low versus CHST9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST9→partner) and Y-score (partner→CHST9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PLLPP1 →	+0.130	+2.673	<.001	.006	3	2
HNSC	SNORA36A →	+0.419	+5.241	<.001	.007	3	2
UCEC	RMND1 →	+0.464	+2.457	<.001	.001	3	2
UCEC	ABHD3 →	+0.504	+3.021	.003	<.001	3	2
LUAD	SUGT1P4 →	+0.330	+6.087	<.001	.002	3	2
UCEC	TRIM73 →	+0.093	+2.021	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,514 associations by consensus.

PLLPP1 by CHST9 expression — COAD

Explore this box plot interactively →