CHST9

Across TCGA patient cohorts, CHST9 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHST9-associated genes across cancer lineages are eIF4E, Rad50, and JNK2. Each is linked with CHST9 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHST9-to-partner and partner-to-CHST9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by CHST9-low versus CHST9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST9→partner) and Y-score (partner→CHST9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.195	+3.335	.007	.005	3	3
UCEC	Rad50 →	-0.180	-2.102	.032	.016	3	2
UCEC	JNK2 →	+0.231	+2.611	<.001	.005	3	1
UCEC	Ku80 →	+0.203	+1.710	.013	.025	3	1
UCEC	MEK1 →	+0.387	+3.087	.002	<.001	3	1
UCEC	p27_pT157 →	-0.053	-1.867	.007	.015	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

eIF4E by CHST9 expression — UCEC

Explore this box plot interactively →