CHST7

Across TCGA pan-cancer cohorts, CHST7 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CHST7 data layer compared with 27 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher CHST7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CHST7 expression acts as an unfavorable survival marker.

LIHC, ESCA, and LUAD are the cancer types where CHST7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.172	0.690	.002	15	view →
ESCA	OS	Median	All	0.198	0.872	.003	12	view →
LUAD	DFS	Median	All	0.049	0.814	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CHST7–LIHC (OS)

Open the LIHC breakdown →