CHST7

Across TCGA patient cohorts, CHST7 mutation is significantly associated with the RNA expression of many other genes, with 3,026 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHST7-associated genes across cancer lineages are PYY3, RNU6-275P, and MIR558. Each is linked with CHST7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST7-to-partner and partner-to-CHST7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PYY3 grouped by CHST7-low versus CHST7-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST7→partner) and Y-score (partner→CHST7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PYY3 →	+0.310	+4.480	<.001	.005	3	2
CESC	RNU6-275P →	+0.270	+4.984	<.001	.003	3	1
CESC	MIR558 →	+0.576	+3.705	<.001	.008	3	1
CESC	MIR549A →	+0.266	+4.757	<.001	.004	3	1
CESC	TRAJ12 →	+0.784	+4.608	<.001	.001	3	1
CESC	RN7SKP263 →	+0.098	+4.984	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,026 associations by consensus.

PYY3 by CHST7 expression — STAD

Explore this box plot interactively →