CHST7

Across TCGA cell cohorts, CHST7 mutation is significantly associated with the drug of many other genes, with 30 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHST7-associated genes across cancer lineages are Nutlin-3a (-), CRT0105446, and Niraparib. Each is linked with CHST7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST7-to-partner and partner-to-CHST7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nutlin-3a (-) grouped by CHST7-low versus CHST7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST7→partner) and Y-score (partner→CHST7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Nutlin-3a (-) →	+0.993	+2.868	.003	.022	3	1
LARGE_INTESTINE	CRT0105446 →	+0.626	+2.652	<.001	.045	3	1
LARGE_INTESTINE	Niraparib →	+0.383	+2.868	.022	.022	3	1
LARGE_INTESTINE	UNC1215 →	+0.278	+2.938	.003	.019	3	1
LARGE_INTESTINE	FGFR_3831 →	+0.583	+2.871	.020	.021	3	1
LARGE_INTESTINE	Luminespib →	+0.887	+2.868	.001	.022	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Nutlin-3a (-) by CHST7 expression — LARGE_INTESTINE

Explore this box plot interactively →