CHST5

Across TCGA patient cohorts, CHST5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,136 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CHST5-associated GO terms across cancer lineages are Intraciliary anterograde transport, Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and Lipoprotein biosynthetic process. Each is linked with CHST5 in more than 25 cancer types. Because this analysis shows association rather than direction, both CHST5-to-partner and partner-to-CHST5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary anterograde transport grouped by CHST5-low versus CHST5-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST5→partner) and Y-score (partner→CHST5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Intraciliary anterograde transport →	+0.100	+0.852	<.001	<.001	3	26
SCLC	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.075	+0.485	<.001	<.001	3	24
DLBC	Lipoprotein biosynthetic process →	+0.049	+0.127	.008	<.001	3	24
ESCA	Cellular response to steroid hormone stimulus →	+0.046	+0.823	.001	.001	3	23
SCLC	Autophagosome maturation →	+0.101	+0.690	<.001	<.001	3	23
SCLC	Transport along microtubule →	+0.049	+0.434	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,136 associations by consensus.

Intraciliary anterograde transport by CHST5 expression — SCLC

Explore this box plot interactively →