CHST5

Across TCGA patient cohorts, CHST5 mutation is significantly associated with the RNA expression of many other genes, with 2,035 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHST5-associated genes across cancer lineages are PDIK1L, RNU6-32P, and RASSF1-AS1. Each is linked with CHST5 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHST5-to-partner and partner-to-CHST5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDIK1L grouped by CHST5-low versus CHST5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST5→partner) and Y-score (partner→CHST5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDIK1L →	+0.358	+2.280	.008	<.001	3	3
UCEC	RNU6-32P →	+0.338	+1.730	.001	.001	3	3
UCEC	RASSF1-AS1 →	+0.431	+2.950	<.001	<.001	3	3
UCEC	LIN7C →	+0.468	+2.628	.001	<.001	3	2
UCEC	COX15 →	+0.502	+2.115	<.001	<.001	3	2
UCEC	SLC7A11 →	+0.778	+1.836	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,035 associations by consensus.

PDIK1L by CHST5 expression — UCEC

Explore this box plot interactively →