CHST5

Across TCGA cell cohorts, CHST5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,187 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CHST5-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, RNA catabolic process, and Nucleic acid catabolic process. Each is linked with CHST5 in more than 9 cancer types. Because this analysis shows association rather than direction, both CHST5-to-partner and partner-to-CHST5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription, elongation grouped by CHST5-low versus CHST5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST5→partner) and Y-score (partner→CHST5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of DNA-templated transcription, elongation →	+0.106	+0.163	<.001	<.001	3	9
BLOOD_Lymphoma	RNA catabolic process →	+0.041	+0.114	.002	.007	2	10
PANCREAS	Nucleic acid catabolic process →	+0.037	+0.123	<.001	<.001	3	9
LUNG_SCLC	mRNA catabolic process →	+0.051	+0.375	<.001	<.001	3	9
LUNG_SCLC	Transport along microtubule →	+0.055	+0.340	<.001	<.001	3	8
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.061	+0.379	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,187 associations by consensus.

Negative regulation of DNA-templated transcription, elongation by CHST5 expression — OESOPHAGUS

Explore this box plot interactively →